Original Article

Comparison of FDG-PET/CT and MR with Diffusion-Weighted Imaging for Assessing Peritoneal Implants in Patients with Gynecologic Neoplasms


  • İrem Erdil
  • Barış Bakır
  • Fatma Yılmaz
  • Rüştü Türkay
  • Mehtap Tunacı
  • Elif Hocaoğlu
  • Yasemin Şanlı

Received Date: 22.05.2014 Accepted Date: 28.04.2014 Eur Arc Med Res 2014;30(3):121-127


Our aim was to determine the sensitivity and comparison of abdominal MRI, diffusion weighted MRI (DWI), PET-CT in detecting peritoneal implants in patients with gynecologic neoplasms.

Material and Methods:

Twenty-one patients with gynecological malignant tumors were enrolled in this retrospective study. Twenty-one oncology patients underwent abdominal and pelvic MRI, diffusion weighted MRI with a b value of 0-500-1000 s/mm² and whole body PET-CT for follow-up. All MRI images were evaluated by a radiologists and PET-CT images were reviewed by a nuclear medicine physician. The results were compared with surgery or laparotomy exploratis, follow-up MRI or CT at a varying time between 2 and 12 months from the initial MRI, and moreover they were also evaluated with laboratory values and clinical outcomes at the 12 to 36th month from the initial MRI.


Forty lesions were identified with PET-CT, forty-nine lesions with MRI and 65 lesions with MRI+DWI. In 8 patients there were no implants with all imaging modalities. Although PET-CT and MRI were negative for two patients, MRI+DWI was positive for them. And also PET-CT was negative for one patient whereas MRI and MRI+DWI was positive. On a lesion-based analysis, overall lesion numbers for PET-CT and MRI+DWI were significantly different (p<0,05).


In our study we found with MRI and MRI+DWI more implants than PET-CT. DWI which may be an alternative to PET-CT with conventional MRI can improve the sensitivity in depicting peritoneal implants.

Keywords: Diffusion weighted MRI, malignancies, gynecologic neoplasms